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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1C
All Species:
22.73
Human Site:
S55
Identified Species:
50
UniProt:
P16403
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16403
NP_005310.1
213
21365
S55
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Chimpanzee
Pan troglodytes
XP_001172525
213
21376
S55
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Rhesus Macaque
Macaca mulatta
P40286
208
22075
V59
L
S
V
S
Q
E
R
V
G
M
S
L
A
A
L
Dog
Lupus familis
XP_853847
290
29282
S110
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
S55
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Rat
Rattus norvegicus
P15865
219
21969
S55
V
A
A
S
K
E
R
S
G
V
S
L
A
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
N55
V
S
V
S
K
E
R
N
G
V
S
L
A
A
L
Chicken
Gallus gallus
P08284
219
22026
K56
V
S
A
S
K
E
R
K
G
L
S
L
A
A
L
Frog
Xenopus laevis
P06892
210
21355
S61
V
S
A
S
K
E
R
S
G
V
S
L
A
A
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
G65
K
N
L
K
E
R
G
G
S
S
L
L
A
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
I62
M
D
R
Q
L
L
F
I
K
R
A
L
K
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
50.7
56.9
N.A.
83.5
84
N.A.
74.4
69.4
58.6
N.A.
N.A.
42.5
N.A.
N.A.
39.4
Protein Similarity:
100
99.5
61.9
60.6
N.A.
84
84.4
N.A.
79.8
73.9
67.1
N.A.
N.A.
52.3
N.A.
N.A.
49.3
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
80
80
93.3
N.A.
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
93.3
100
N.A.
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
64
0
0
0
0
0
0
0
10
0
91
82
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
82
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
82
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
10
73
0
0
10
10
0
0
0
10
0
10
% K
% Leu:
10
0
10
0
10
10
0
0
0
10
10
100
0
0
82
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
82
0
0
10
0
0
0
0
0
% R
% Ser:
0
37
0
82
0
0
0
55
10
10
82
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
73
0
19
0
0
0
0
10
0
64
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _